The newlywed couple was reportedly on a cruise that stopped in the popular tourist destination, about 257 kilometres from Tegucigalpa.
The Israeli couple were rushed to hospital where the husband died shortly afterwards. She is now in a stable condition, reports USA Today.
A newly Wednesday Israeli man was killed and his wife seriously injured in a zip-lining accident during their honeymoon in Honduras.
"The young man complained that he could not breathe", Guerrero said.
The couple booked the Extreme Caribe Zip Line Tour through the Royal Caribbean website, according to a local firefighter.
An investigation has been launched into how the accident occurred.
The Israeli Foreign Ministry said that it is arranging for Mr Tishman's body to be flown back to his home country.
This is not the only incident of serious injury or death while zip-lining in Roatan.
"Swoop above exotic plants, giant African Palms and lovely landscapes", reads the Royal Caribbean online description of the zip-line tour, which consists of 12 zip lines, double gliding parallel cables, 18 platforms and four hiking trails. As of 2012, there are over 200.
According to Jim Walker, a lawyer who specializes in maritime litigation, this is not the first time a zip-line excursion in Roatan has resulted in injuries.
There have been no further updates on her current status.
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